تفاعل #1876820

معادلة التفاعل

1,3,5-trihydroxyadamantane

trimethylamine

trimethylsilyl chloride

→

1,3-dihydroxy-5-trimethylsiloxyadamantane

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   أخرىReaction
2. 2
   أخرىwas carried out at room temperature
3. 3
   أخرىThe reaction product was partitioned by high performance liquid chromatography

الإجراء التجريبي

This 1,3,5-trihydroxyadamantane was dissolved in methylene chloride. To this solution were added a small amount of trimethylamine, and then an equimolar amount of trimethylsilyl chloride. Reaction was carried out at room temperature. The reaction product was partitioned by high performance liquid chromatography to obtain 1,3-dihydroxy-5-trimethylsiloxyadamantane.

المصدر