تفاعل #1869149

ord-f4736c1983ad4437920881e9356b17a0

معادلة التفاعل

C=CCCCCCCCCC(=O)O
10-undecenoic acid
O=C(Cl)C(=O)Cl
(COCl)2
C=CCCCCCCCCC(=O)Cl
10-undecenoyl chloride
المردود 100.0%

المتفاعلات

الكواشف

لا شيء

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىThe solvent was removed under reduced pressure

الإجراء التجريبي

To a stirred solution of 10-undecenoic acid (5.055 mL, 25 mmol) in CH2Cl2 (50 mL) was slowly added (COCl)2 (4.364 mL, 50 mmol). The mixture was stirred at room temperature overnight. The solvent was removed under reduced pressure to give 10-undecenoyl chloride (25 mmol). The product was used for the next reaction without further purification. 1H NMR (500 MHz, CDCl3) δ 1.29-1.48 (m, 10H), 1.71 (m, 2H), 2.05 (m, 2H), 2.88 (t, J=7 Hz, 2H), 4.98 (m, 2H), 5.80 (m, 1H).

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07498292B2uspto-grants-2009_03