تفاعل #1853178

معادلة التفاعل

3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester

1-cyclopropyl-7-fluoro-9-methyl-4-oxo-8-piperazin-1-yl-4H-quinolizine-3-carboxylic acid

8-(3-aminomethyl-pyrrolidin-1-yl)-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4H-quinolizine-3-carboxylic acid

→

title compound

(R/S)-8-[4-(1-tert-Butoxycarbonyl-pyrrolidin-3-yl)-piperazin-1-yl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4H-quinolizine-3-carboxylic acid

ظروف التفاعل

الإجراء التجريبي

The title compound was prepared as described in Step 1 of Example 9 (1974) except 3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester was used in place of 4-oxo-piperidine-1-carboxylic acid tert-butyl ester and 1-cyclopropyl-7-fluoro-9-methyl-4-oxo-8-piperazin-1-yl-4H-quinolizine-3-carboxylic acid was used in place of (8-(3-aminomethyl-pyrrolidin-1-yl)-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4H-quinolizine-3-carboxylic acid.

المصدر