تفاعل #1833305

معادلة التفاعل

furo[3,2-b]pyridin-6-ol

furo[3,2-b]pyridin-6-ol

6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furo[3,2-b]pyridine

→

6-(4,5-dihydroisoxazol-3-yloxy)furo[3,2-b]pyridine

ظروف التفاعل

المعالجة

1. 1
   أخرىThese compounds can be separated

الإجراء التجريبي

6-(4,5-dihydroisoxazol-3-yloxy)furo[3,2-b]pyridine I-69a and I-69b were prepared in 2 steps from racemic compound I-10 and furo[3,2-b]pyridin-6-ol using Method 5 after furo[3,2-b]pyridin-6-ol is prepared from 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furo[3,2-b]pyridine using Method 11. These compounds can be separated using chiral HPLC methods known in the art. For example, see chiral HPLC Method disclosed herein. [M+H]+=374.2 m/z. Activity: A

المصدر