تفاعل #1811886

معادلة التفاعل

[(2R)-8-ethoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl]methyl 4-methylbenzenesulfonate

cis-3-(5-fluoro-1H-indol-3-yl)-cyclopentylamine

→

title compound

المردود 64.0%

N-{[(2S)-8-ethoxy-2,3-dihydro-1,4-benzodioxin-2-yl]methyl}-N-[(cis)-3-(5-fluoro-1H-indol-3-yl)cyclopentyl]amine

المردود 64.0%

ظروف التفاعل

المعالجة

1. 1
   أخرىThis compound was prepared in the same manner as for Example 1

الإجراء التجريبي

This compound was prepared in the same manner as for Example 1, using [(2R)-8-ethoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl]methyl 4-methylbenzenesulfonate (0.25 g, 0.68 mmol) and cis-3-(5-fluoro-1H-indol-3-yl)-cyclopentylamine (0.3 g, 1.38 mmol), to afford 0.16 g (64%) of the title compound as its hydrochloride salt: MS (ESI) m/z 411 [M+H]+.

المصدر