تفاعل #1811

معادلة التفاعل

ammonia

isothiocyanatoacetaldehyde dimethyl acetal

→

title compound

N-(2,2-Dimethoxyethyl)thiourea

المذيبات

Methanol

ظروف التفاعل

المعالجة

1. 1
   تركيزThe mixture was concentrated
2. 2
   أخرىthe residue was chromatographed (silica gel, 5% methanol/dichloromethane)

الإجراء التجريبي

Methanol (200 mL) was saturated with ammonia and stirred with isothiocyanatoacetaldehyde dimethyl acetal (5.0 g) for 2 h. The mixture was concentrated and the residue was chromatographed (silica gel, 5% methanol/dichloromethane) to give the title compound.

المصدر