تفاعل #1794077

معادلة التفاعل

1-[2-(4-chlorophenyl)ethyl]-ethanediol

2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane

4-methylbenzenesulfonic acid

butanol

→

2-(bromomethyl)-4-[2-(4-chlorophenyl)ethyl]-2-(2,4-dichlorophenyl)-1,3-dioxolane

المذيبات

water

methylbenzene

ظروف التفاعل

المعالجة

1. 1
   أخرىThe reaction mixture is evaporated
2. 2
   workup.DISSOLUTIONthe residue is dissolved in 2,2'-oxybispropane
3. 3
   workup.STIRRINGThe solution is stirred with silica gel
4. 4
   ترشيحThe latter is filtered off
5. 5
   أخرىthe filtrate is evaporated

الإجراء التجريبي

A mixture of 11.2 parts of 1-[2-(4-chlorophenyl)ethyl]-ethanediol, 15.6 parts of 2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane, 4 parts of 4-methylbenzenesulfonic acid, 40 parts of butanol and 225 parts of methylbenzene is stirred and refluxed for 5 days with water-separator. The reaction mixture is evaporated and the residue is dissolved in 2,2'-oxybispropane. The solution is stirred with silica gel. The latter is filtered off and the filtrate is evaporated, yielding 2-(bromomethyl)-4-[2-(4-chlorophenyl)ethyl]-2-(2,4-dichlorophenyl)-1,3-dioxolane as a residue.

المصدر