تفاعل #1782840

معادلة التفاعل

rac-N2-(7-methoxy-indan-1-yl)-4H-benzo[d][1,3]oxazine-2,6-diamine

rac-N2-(7-Methoxy-indan-1-yl)-4H-benzo[d][1,3]oxazine-2,6-diamine

benzenesulfonyl chloride

→

title compound

المردود 26.0%

rac-N-[2-(7-Methoxy-indan-1-ylamino)-4H-benzo[d][1,3]oxazin-6-yl]-benzenesulfonamide

المردود 26.0%

ظروف التفاعل

الإجراء التجريبي

Prepared from rac-N2-(7-methoxy-indan-1-yl)-4H-benzo[d][1,3]oxazine-2,6-diamine (Example 10) (155 mg, 0.50 mmol, HPLC 0.776 min) and benzenesulfonyl chloride (70 ul, 0.55 mmol) according to the procedure described for Example 27. Obtained the title compound as an off-white solid (58 mg, 26%, HPLC 1.576 min), MS (ISP) m/e=450.2 [(M+H)+].

المصدر