تفاعل #1782839

معادلة التفاعل

rac-N2-(7-methoxy-indan-1-yl)-4H-benzo[d][1,3]oxazine-2,6-diamine

rac-N2-(7-Methoxy-indan-1-yl)-4H-benzo[d][1,3]oxazine-2,6-diamine

cyclopropanesulfonyl chloride

→

title compound

المردود 61.4%

rac-Cyclopropanesulfonic acid [2-(7-methoxy-indan-1-ylamino)-4H-benzo[d][1,3]oxazin-6-yl]-amide

المردود 61.4%

ظروف التفاعل

الإجراء التجريبي

Prepared from rac-N2-(7-methoxy-indan-1-yl)-4H-benzo[d][1,3]oxazine-2,6-diamine (Example 10) (155 mg, 0.50 mmol, HPLC 0.776 min) and cyclopropanesulfonyl chloride (77 mg, 0.55 mmol) according to the procedure described for Example 27. Obtained the title compound as a light brown solid (127 mg, 61%, HPLC 1.366 min), MS (ISP) m/e=414.2 [(M+H)+].

المصدر