تفاعل #1782823

معادلة التفاعل

rac-(6-bromo-4H- benzo[d][1,3]oxazin-2-yl)-(7-methoxy-indan-1-yl)-amine

rac-(6-Bromo-4H-benzo[d][1,3]oxazin-2-yl)-(7-methoxy-indan-1-yl)-amine

2-amino-6-trifluoromethyl-pyridine

→

title compound

المردود 63.4%

rac-N2-(7-Methoxy-indan-1-yl)-N6-(6-trifluoromethyl-pyridin-2-yl)-4H-benzo[d][1,3]oxazine-2,6-diamine

المردود 63.4%

ظروف التفاعل

الإجراء التجريبي

The title compound (144 mg, 63%), light brown foam, MS (ISP): m/e=455.3 (M+H+), was prepared in accordance with the general method of Example 35 from rac-(6-bromo-4H- benzo[d][1,3]oxazin-2-yl)-(7-methoxy-indan-1-yl)-amine (Example 74) (187 mg, 0.5 mmol) an commercially available 2-amino-6-trifluoromethyl-pyridine (162 mg, 1.0 mmol).

المصدر