تفاعل #1782820

معادلة التفاعل

(5-bromo-2-isothiocyanato-benzyloxy)-tert-butyl-dimethyl-silane

rac-7-methoxy-indan-1-ylamine

rac-7-Methoxy-indan-1-ylamine

→

title compound

المردود 67.0%

rac-(6-Bromo-4H-benzo[d][1,3]oxazin-2-yl)-(7-methoxy-indan-1-yl)-amine

المردود 67.0%

ظروف التفاعل

الإجراء التجريبي

Prepared from (5-bromo-2-isothiocyanato-benzyloxy)-tert-butyl-dimethyl-silane (Example 32, step B) (4.0 g, 11.2 mmol) and the rac-7-methoxy-indan-1-ylamine (Example 10, step A) (1.82 g, 11.2 mmol) according to the procedure described for Example 1. Obtained the title compound as a white solid (2.79 g, 67%), m.p. 151° C.; MS (ISP) m/e=375.1 [(M+H)+].

المصدر