تفاعل #1782808

معادلة التفاعل

rac-(6-bromo-4H-benzo[d][1,3]oxazin-2-yl)-(4-methoxy-2,3-dihydro-benzofuran-3-yl)-amine

rac-(6-Bromo-4H-benzo[d][1,3]oxazin-2-yl)-(4-methoxy-2,3-dihydro-benzofuran-3-yl)-amine

2-amino-6-trifluoromethyl-pyridine

→

title compound

المردود 12.3%

rac-N2-(4-Methoxy-2,3-dihydro-benzofuran-3-yl)-N6-(6-trifluoromethyl-pyridin-2-yl)-4H-benzo[d][1,3]oxazine-2,6-diamine

المردود 12.3%

ظروف التفاعل

الإجراء التجريبي

The title compound (28 mg, 12%), light brown foam, MS (ISP): m/e=457.3 (M+H+), was prepared in accordance with the general method of Example 35 from rac-(6-bromo-4H-benzo[d][1,3]oxazin-2-yl)-(4-methoxy-2,3-dihydro-benzofuran-3-yl)-amine (Example 54) (188 mg, 0.5 mmol) and commercially available 2-amino-6-trifluoromethyl-pyridine (162 mg, 1.0 mmol).

المصدر