تفاعل #1782804

ord-49cbdaded86a40ae909280ecd5fe6464

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىPrepared from the

الإجراء التجريبي

Prepared from the above described rac-2-chloro-N-[2-(7-methoxy-indan-1-ylamino)-4H-benzo[d][1,3]oxazin-6-yl]-acetamide (100 mg, 0.259 mmol) and morpholine (226 ul, 2.59 mmol) in acetonitrile (1 ml) according to the procedure described for Example 3 step B. Obtained the title compound as an off-white foam (110 mg, 97%), MS (ISP) m/e=437.2 [(M+H)+].

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08163740B2uspto-grants-2012_04