تفاعل #1772061

معادلة التفاعل

4-Hydroxy styrene

urea hydrogen peroxide

2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid monohydrate

→

4-hydroxyphenyloxirane

المردود 66.0%

المذيبات

dichloromethane tetrahydrofuran

ظروف التفاعل

المعالجة

1. 1
   أخرىReaction time
2. 2
   أخرى20 hours, Yield: 66%

الإجراء التجريبي

Fifth recycle 4-Hydroxy styrene: 1 g, 8.3 mmol, urea hydrogen peroxide: 3 g, 32 mmol, Immobilized lipase: 87 mg, 2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid monohydrate: 0.3 g, 1.03 mmol, dry dichloromethane:tetrahydrofuran (4:1): 15 mL. Same procedure was followed as described in example ‘1’. Reaction time: 20 hours, Yield: 66%.

المصدر