تفاعل #1771990

ord-56238b79bf8e4876a8c816dff94dc2f6

معادلة التفاعل

CC1(C)CN(C(=O)OC(C)(C)C)[C@@](C(=O)O)(C(C)(C)C)C1
tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline
→
CC1(C)CN[C@H](C(=O)O)C1
4,4-Dimethylproline

المتفاعلات

CC1(C)CN(C(=O)OC(C)(C)C)[C@@](C(=O)O)(C(C)(C)C)C1
tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline

الكواشف

لا شيء

المذيبات

ClCCl
dichloromethane

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    تركيزThe solution was concentrated
  2. 2
    أخرىdried under high vacuum
  3. 3
    أخرىtaken to the next step without further purification

الإجراء التجريبي

A solution of tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline in dichloromethane (5 mL) and trifluoroacetic (5 mL) was stirred at room temperature for five hours. The solution was concentrated, dried under high vacuum and taken to the next step without further purification.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: USRE043298E1uspto-grants-2012_04