تفاعل #1764380

معادلة التفاعل

(4-Bromo-phenyl)-cyclopropyl-methanone

(4-carboxy-3-fluorophenyl)boronic acid

2-(R)-Methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine

→

title compound

Cyclopropyl-{3′-fluoro-4′-[2-(S)-(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidine-1-carbonyl]-biphenyl-4-yl}-methanone

ظروف التفاعل

الإجراء التجريبي

The title compound is prepared in a manner substantially analogous to Procedures QQ and B′ starting from commercially available (4-Bromo-phenyl)-cyclopropyl-methanone and (4-carboxy-3-fluorophenyl)boronic acid (CAS#120153-08-4), then 2-(R)-Methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine. MS (M+H) 435.2

المصدر