تفاعل #1761875

معادلة التفاعل

Intermediate 14

(RS)-N-(Ethoxycarbonyl)-S-(3-{[5-bromo-4-(methoxy)pyrimidin-2-yl]amino}phenyl)-S-methylsulfoximide

4-ethoxypyrimidine

→

desired product

المردود 3.0%

(RS)-S-(3-{[5-bromo-4-(methoxy)pyrimidin-2-yl]amino}phenyl)-S-methylsulfoximide

المردود 3.0%

ظروف التفاعل

المعالجة

1. 1
   أخرىto give

الإجراء التجريبي

Intermediate 14a was prepared in analogy to GP 9 by reaction of Intermediate 14 (500 mg (1.16 mmol) to give, aside a larger quantity of the corresponding 4-ethoxypyrimidine, 14 mg (3%) of the desired product.

المصدر