تفاعل #1726667

معادلة التفاعل

Dibenzothiophene

hydrogen peroxide

water

→

dibenzothiophene-S-oxide

المذيبات

trifluoroacetic acid

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwhile cooling with ice so as
2. 2
   أخرىAfter the reaction
3. 3
   أخرىto precipitate crystals
4. 4
   ترشيحThe crystals are recovered by filtration
5. 5
   غسيلwashed with water
6. 6
   أخرىThe obtained crystals are recrystallized with acetonitrile

الإجراء التجريبي

Dibenzothiophene (20.0 g) is suspended in 80.0 ml of trifluoroacetic acid at room temperature. Into the suspension is slowly dropped 12.4 ml of 30% aqueous hydrogen peroxide while cooling with ice so as to maintain the reaction temperature around 60° C. After completion of dropping, the reaction solution is stirred at room temperature for 30 minutes. After the reaction, the reaction solution is added to 1,000 ml of water to precipitate crystals. The crystals are recovered by filtration and washed with water. The obtained crystals are recrystallized with acetonitrile to obtain 19.2 g of dibenzothiophene-S-oxide.

المصدر