تفاعل #1715
ord-6d542e3dbdd248a898a4ea74dbd0c2eb
معادلة التفاعل
N-(1-butyl-4-piperidinyl)methylamine
5-Chloro-2-methylbenzoxazole-7-carboxylic acid
oxalyl chloride
→
title compound
N-[(1-Butyl-4-piperidinyl)methyl]5-chloro-2-methylbenzoxazole-7-carboxamide
المتفاعلات
الكواشف
لا شيء
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
الإجراء التجريبي
5-Chloro-2-methylbenzoxazole-7-carboxylic acid (Ger. Offen. 2,225,544) is converted to its acid chloride by treatment with oxalyl chloride. The acid chloride is treated with N-(1-butyl-4-piperidinyl)methylamine in the presence of triethylamine to afford the title compound.