تفاعل #170678

معادلة التفاعل

water

3-aminopyrazole

2,5-hexanedione

→

titled compound

3-(2,5-Dimethylpyrrol-1-yl)-1H-pyrazole

المذيبات

acetic acid

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةat reflux
2. 2
   ترشيحthe precipitated solid was collected by filtration
3. 3
   غسيلThe resulting solid was washed with water (1000 ml)
4. 4
   أخرىdried under reduced pressure

الإجراء التجريبي

To a solution of 3-aminopyrazole (100 g) in acetic acid (1000 ml) was added 2,5-hexanedione (148 ml), and the mixture was stirred for 2.4 hours at reflux. This reaction solution was cooled to room temperature, water (1000 ml) was added thereto, and the precipitated solid was collected by filtration. The resulting solid was washed with water (1000 ml), and dried under reduced pressure to give the titled compound (183 g).

المصدر