تفاعل #170523
ord-1f79af4c6aa64cda9735517091a3e5e0
معادلة التفاعل
6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid
2-methyl-pyrrolidine
→
title compound
المردود 99.0%
[6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridin-3-yl]-(2-methyl-pyrrolidin-1-yl)-methanone
المردود 99.0%
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
الإجراء التجريبي
As described for example 191, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (200 mg, 0.64 mmol) was converted, using 2-methyl-pyrrolidine instead of 2-aminoethyl isopropylether, to the title compound (240 mg, 99%) which was obtained as a colourless. MS: m/e=378.3 [M+H]+.