تفاعل #170508

معادلة التفاعل

6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid

2-amino-1,3-propandiol

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title compound

المردود 87.0%

N-(2-Hydroxy-1-hydroxymethyl-ethyl)-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinamide

المردود 87.0%

ظروف التفاعل

الإجراء التجريبي

As described for example 191, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (200 mg, 0.65 mmol) was converted, using 2-amino-1,3-propandiol instead of 2-aminoethyl isopropylether, to the title compound (215 mg, 87%) which was obtained as a colourless oil. MS: m/e=384.0 [M+H]+.

المصدر