تفاعل #170371

معادلة التفاعل

6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid

6-oxa-1-aza-spiro[3.3]heptane

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title compound

المردود 35.0%

[6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridin-3-yl]-(6-oxa-1-aza-spiro[3.3]hept-1-yl)-methanone

المردود 35.0%

ظروف التفاعل

الإجراء التجريبي

As described for example 15, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (33 mg, 0.1 mmol) was converted, using 6-oxa-1-aza-spiro[3.3]heptane instead of 3-methoxypropylamine, to the title compound (15 mg, 35%) which was obtained as a colourless gum. MS: m/e=392.3 [M+H]+.

المصدر