تفاعل #170203

معادلة التفاعل

bromine

2-amino-3-pyridinecarboxaldehyde

→

title compound

المردود 165.3%

2-Amino-5-bromonicotinaldehyde hydrobromide

المردود 165.3%

المذيبات

acetic acid

acetic acid

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe resulting precipitate was filtered
2. 2
   غسيلwashed with diethyl ether

الإجراء التجريبي

A solution of bromine (1.05 mL, 20.0 mmol) in acetic acid (20 mL) was added to a solution of 2-amino-3-pyridinecarboxaldehyde (2.5 g, 20 mmol) in acetic acid (50 mL) at room temperature. The reaction mixture was then stirred overnight. The resulting precipitate was filtered and washed with diethyl ether to give the title compound as a white solid (4.66 g, 80%).

المصدر