تفاعل #1687669

ord-7350acecf0d24cf6aec1847009ff1ca8

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    درجة الحرارةwas maintained
  2. 2
    درجة الحرارةat reflux for 1 hour
  3. 3
    درجة الحرارةThe mixture was cooled
  4. 4
    غسيلwas rinsed with ethanol
  5. 5
    تركيزThe fluids were concentrated
  6. 6
    أخرىthe resulting product was recrystallized from a 50/50 water/ethanol mixture

الإجراء التجريبي

A mixture of 12 g of benzyl 2-hydroxy-4-(2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)-oxy]disiloxanyl]propyloxy]benzoate (0.023 mol), ethanol (40 ml), cyclohexene (12 ml) and 10% palladium-on-charcoal (1.2 g) was maintained at reflux for 1 hour. The mixture was cooled and was rinsed with ethanol. The fluids were concentrated and the resulting product was recrystallized from a 50/50 water/ethanol mixture to give the 2-hydroxy-4-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl]propyloxy]benzoic acid in the form of a white powder.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05976558uspto-grants-1999_11