تفاعل #1687647

ord-8eb39357567449b8b708235f99951a97

معادلة التفاعل

CCC(CC)OC(=O)c1ccc(OC(C)=O)cc1F
( 3 )
CCC(CC)OC(=O)c1ccc(OC(C)=O)cc1F
4-acetoxy-2-fluoro-1-(1-ethylpropyloxycarbonyl)benzene
NCc1ccccc1
benzylamine
CCC(CC)OC(=O)c1ccc(O)cc1F
4-hydroxy-2-fluoro-1-(1-ethylpropyloxycarbonyl)benzene

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    غسيلthe diluted mixture was washed with diluted hydrochloric acid
  2. 2
    تجفيفwith water and dried over magnesium sulfate

الإجراء التجريبي

0.5 Gram of the compound obtained in the above (3) was dissolved in 30 ml of ethanol, and 1.5 g of benzylamine was added dropwise thereto. Further, the mixture was stirred at room temperature for one day and diluted with 300 ml of ether, and the diluted mixture was washed with diluted hydrochloric acid and then with water and dried over magnesium sulfate.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05976409uspto-grants-1999_11