تفاعل #1687619

معادلة التفاعل

3-Cyanopyridine

methyl iodide

methyl iodide

→

title compound

المردود 81.0%

3-Cyano-1-methylpyridinium Iodide

المردود 81.0%

المذيبات

acetone

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe mixture was filtered
2. 2
   غسيلthe solid product was washed with acetone (100 ml)
3. 3
   أخرىAfter drying

الإجراء التجريبي

3-Cyanopyridine (1) (104 g, 1 mol) and methyl iodide (150 g, 1.06 mol) in acetone (500 ml) was stirred for 5 hours at room temperature. Then more methyl iodide (20 g, 0.14 mol) was added, and the reaction mixture was stirred overnight at room temperature. The mixture was filtered and the solid product was washed with acetone (100 ml) and then thoroughly with ether. After drying, 199 g (0.81 mol, 81%) of the title compound were obtained, M.P. 145°-150° C.

المصدر