تفاعل #166076

معادلة التفاعل

1,1-diphenyl-hex-5-en-2-ol

2-benzhydryl-2,3-dihydro-4H-pyran-4-one

ethyl vinyl ether

NaHCO3

→

1,1-diphenyl-2-(1-ethenoxy)-hex-5-ene

المردود 66.0%

ظروف التفاعل

المعالجة

1. 1
   أخرىThe organic phase was separated
2. 2
   استخلاصthe aqueous layer was extracted with ethyl ether
3. 3
   تجفيفdried over anhydrous Na2SO4
4. 4
   أخرىRemoval of the solvent and purification by flash chromatography (Hexane/Ethyl Acetate 20:1)

الإجراء التجريبي

Into a mixture of 1,1-diphenyl-hex-5-en-2-ol 2 (7 g, 27.78 mmol) in ethyl vinyl ether (250 ml) was added Hg(OCOCF3)2(2.37 g, 5.56 mmol) and was stirred overnight at room temperature. The reaction mixture was neutralized by addition of sat. aqueous NaHCO3. The organic phase was separated and the aqueous layer was extracted with ethyl ether, and dried over anhydrous Na2SO4. Removal of the solvent and purification by flash chromatography (Hexane/Ethyl Acetate 20:1) gave 1,1-diphenyl-2-(1-ethenoxy)-hex-5-ene 9 (5.1 g, 66%) as a liquid.

المصدر