تفاعل #164024

معادلة التفاعل

L-tert-leucine

diisopropyl ether

→

D-tert-leucine

المردود 90.0%

المذيبات

acetone

ظروف التفاعل

المعالجة

1. 1
   أخرىto remove any traces of dibenzoyl-d-tartaric acid
2. 2
   تركيزwas concentrated under reduced pressure at 55° C
3. 3
   أخرىThe residue obtained
4. 4
   ترشيحfiltered

الإجراء التجريبي

The filtrate obtained at dibenzoyl-d-tartrate salt stage (step.ii), was treated with a small amount of diisopropyl ether to remove any traces of dibenzoyl-d-tartaric acid and was concentrated under reduced pressure at 55° C. The residue obtained was stirred with small amount of acetone and filtered to obtain D-tert-leucine as a colorless solid (90% yield, 98.8% D-tert-leucine and 1.2% L-tert-leucine).

المصدر