تفاعل #163995

معادلة التفاعل

2-(cyanomethyl)-3-ethyl-1,3-benzothiazol-3-ium iodide

(2Z)-2-[(2E)-3-methoxyprop-2-en-1-ylidene]-1-benzothiophen-3-(2H)-one 1,1-dioxide

CHCl3 MeOH

sodium acetate

→

(2E,3E,5Z)-5-(1,1-dioxido-3-oxo-1-benzothien-2(3H)-ylidene)-2-(3-ethyl-1,3-benzothiazol-2(3H)-ylidene)pent-3-enenitrile

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىIn a one-necked round bottom 100-mL flask equipped with magnetic stir bar
2. 2
   درجة الحرارةreflux condenser
3. 3
   درجة الحرارةThe flask was heated on an oil bath
4. 4
   درجة الحرارةunder reflux for an additional 30 min
5. 5
   ترشيحthe precipitated solid was filtered
6. 6
   غسيلwashed with methanol
7. 7
   أخرىdried

الإجراء التجريبي

In a one-necked round bottom 100-mL flask equipped with magnetic stir bar and reflux condenser were added 2-(cyanomethyl)-3-ethyl-1,3-benzothiazol-3-ium iodide (1.00 g, 3.03 mmol), (2Z)-2-[(2E)-3-methoxyprop-2-en-1-ylidene]-1-benzothiophen-3-(2H)-one 1,1-dioxide (1.00 g, 4.00 mmol) and CHCl3-MeOH mixture (1:1, 20 mL). The flask was heated on an oil bath with stirring until boiling began, and a solution of sodium acetate (320 mg, 4.00 mmol) in 10 mL of methanol was added to the flask. The stirring was continued under reflux for an additional 30 min. The flask was cooled to room temperature and the precipitated solid was filtered, washed with methanol and dried. Green crystals. The yield was 730 mg (57% of theory).

المصدر