تفاعل #163487

ord-c829ad5c8c004e5c85e2ea643e0ba45b

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    ترشيحfiltered
  2. 2
    تركيزconcentrated

الإجراء التجريبي

To a suspension of 1-fluoro-2-methylpropan-2-amine hydrochloride (ABCR) (2 g, 15.7 mmol), anhydrous magnesium sulfate (3.77 g, 31.4 mmol) and potassium carbonate (2.17 g, 15.68 mmol) in dichloromethane (100 mL) was added drop wise hexanal (1.93 mL, 15.7 mmol) at 0° C. The reaction mixture was stirred for 10 h at room temperature, then filtered and concentrated to obtain the title compound as a pale yellow liquid.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08835475B2uspto-grants-2014_09