تفاعل #161722

معادلة التفاعل

4,5-difluoro-1,3-dihydro-indol-2-one

acetic anhydride

→

1-acetyl-4,5-difluoro-1,3-dihydro-indol-2-one

ظروف التفاعل

المعالجة

1. 1
   ترشيحfiltered
2. 2
   غسيلwashed with water
3. 3
   أخرىThe product was recrystallised from a mixture of water and ethanol, suction
4. 4
   ترشيحfiltered
5. 5
   أخرىdried

الإجراء التجريبي

2.00 g (11.8 mmol) 4,5-difluoro-1,3-dihydro-indol-2-one I were stirred in 6.62 mL (55.0 mmol) acetic anhydride for 2 h at 150° C. The reaction mixture was added to ice water, the precipitated solid was suction filtered and washed with water. The product was recrystallised from a mixture of water and ethanol, suction filtered and dried.

المصدر