تفاعل #161700

معادلة التفاعل

hydrochloric acid

cyclobutanecarboxylic acid chloride

phenylhydrazine

pyridine

→

Cyclobutanecarboxylic acid N′-phenylhydrazide

المذيبات

DMF

ظروف التفاعل

المعالجة

1. 1
   ترشيحfiltered
2. 2
   غسيلwashed with 50 mL water
3. 3
   أخرىdried i
4. 4
   استخلاصThe product was extracted with 50 mL ether and suction
5. 5
   ترشيحfiltered
6. 6
   غسيلThe solid was washed with 20 mL ether
7. 7
   أخرىdried in the air

الإجراء التجريبي

3.54 mL (31.0 mmol) cyclobutanecarboxylic acid chloride were added dropwise at RT to 3.00 mL (30.2 mmol) phenylhydrazine and 4.75 mL (60.0 mmol) pyridine in 30 mL DMF. The mixture was stirred for 1 h at RT and poured onto 200 mL of a 1M hydrochloric acid solution. The precipitated solid was suction filtered, washed with 50 mL water and dried i. vac. The product was extracted with 50 mL ether and suction filtered. The solid was washed with 20 mL ether and dried in the air.

المصدر