تفاعل #161019

معادلة التفاعل

1-aminocyclohexanecarboxylic acid ethyl ester hydrochloride

4-(4-propylpiperazin-1-yl)benzoic acid hydrochloride

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title compound

المردود 65.0%

1-[[[4-(4-Propylpiperazin-1-yl)phenyl]carbonyl]amino]cyclohexanecarboxylic acid ethyl ester

المردود 65.0%

ظروف التفاعل

الإجراء التجريبي

741 mg (3.57 mmol) of 1-aminocyclohexanecarboxylic acid ethyl ester hydrochloride was used instead of 1-aminocyclohexanecarboxylic acid methyl ester hydrochloride, and 1.00 g (3.57 mmol) of 4-(4-propylpiperazin-1-yl)benzoic acid hydrochloride was used instead of 3-furancarboxylic acid in the process according to Reference Example 15 to obtain 928 mg (65%) of the title compound.

المصدر