تفاعل #161017

معادلة التفاعل

hydrochloric acid ethyl acetate

1-[[[4-(4-propylpiperazin-1-yl)phenyl]carbonyl]amino]cyclohexanecarboxylic acid methyl ester

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title compound

المردود 66.0%

1-[[[4-(4-Propylpiperazin-1-yl)phenyl]carbonyl]amino]cyclohexanecarboxylic acid methyl ester hydrochloride

المردود 66.0%

المذيبات

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe precipitated crystal was collected by filtration

الإجراء التجريبي

1 ml of 4N hydrochloric acid/ethyl acetate solution was added to a solution of 120 mg (0.31 mmol) of 1-[[[4-(4-propylpiperazin-1-yl)phenyl]carbonyl]amino]cyclohexanecarboxylic acid methyl ester in 10 ml of ethyl acetate, and the mixture was stirred at room temperature for 30 minutes. The precipitated crystal was collected by filtration to obtain 87 mg (66%) of the title compound.

المصدر