تفاعل #160606

معادلة التفاعل

5,6-difluoro-N1-(4-fluoro-2-iodophenyl)-3-methoxybenzene-1,2-diamine

1,1′-Carbonyldiimidazole

→

6,7-Difluoro-1-(4-fluoro-2-iodophenyl)-4-methoxy-1H-benzo[d]imidazol-2(3H)-one

المذيبات

CH2Cl2

ظروف التفاعل

المعالجة

1. 1
   أخرىprecipitated out
2. 2
   ترشيحThe white solid was filtered
3. 3
   أخرىused further without any purification

الإجراء التجريبي

To the stirred solution of 5,6-difluoro-N1-(4-fluoro-2-iodophenyl)-3-methoxybenzene-1,2-diamine (0.17 gm, 0.43 mmol) in CH2Cl2 (2 ml), 1,1′-Carbonyldiimidazole (0.085 gm, 0.53 mmol) was added. This reaction mixture was kept stirring at room temperature for 16 hours when product precipitated out. The white solid was filtered and used further without any purification. (0.089 gm); m/z=419 [M−1]−.

المصدر