تفاعل #1605811

معادلة التفاعل

2-Phenylaniline

acetic anhydride

→

2-phenyl-N-acetylaniline

المردود 99.5%

المذيبات

acetic acid

ظروف التفاعل

المعالجة

1. 1
   تركيزThe solution was concentrated under reduced pressure
2. 2
   workup.ADDITIONto the residue was added water (15 mL)
3. 3
   workup.STIRRINGthe mixture was stirred at room temperature for 3 hours
4. 4
   ترشيحThe precipitate was collected by filtration
5. 5
   غسيلwashed with purified water
6. 6
   أخرىdried under reduced pressure

الإجراء التجريبي

2-Phenylaniline (5 g, 29.55 mmol) was dissolved in acetic acid (30 mL), acetic anhydride (3.62 g, 35.45 mmol) was added thereto under ice bath, and the mixture was stirred under ice bath for 2 hours. The solution was concentrated under reduced pressure. to the residue was added water (15 mL), and the mixture was stirred at room temperature for 3 hours. The precipitate was collected by filtration, washed with purified water, and dried under reduced pressure to obtain 2-phenyl-N-acetylaniline (6.21 g).

المصدر