تفاعل #1602570

معادلة التفاعل

sodium 1,1-difluoro-2-(valeryloxy)ethanesulfonate

sodium 2-valeryloxy-1,1-difluoroethane sulfonate

triphenylsulfonium chloride

triphenylsulfonium chloride

→

triphenylsulfonium 1,1-difluoro-2-(valeryloxy)ethanesulfonate

المردود 64.0%

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   استخلاصThen, extraction
2. 2
   workup.ADDITIONby adding 30 mL of chloroform
3. 3
   غسيلThe obtained organic layer was rinsed two times with water
4. 4
   workup.DISTILLATIONby distilling a solvent off,

الإجراء التجريبي

A 100 mL reactor was charged with 3.0 g (26% purity, 2.9 millimoles) of sodium 1,1-difluoro-2-(valeryloxy)ethanesulfonate obtained in Example 5-3 and 30 g of water, followed by adding dropwise an aqueous solution of triphenylsulfonium chloride [17.8 g (5.2 millimoles/1.8 equivalents) of triphenylsulfonium chloride and 16.2 g of water] at room temperature, followed by stirring at room temperature for 1.5 hours. Then, extraction was conducted by adding 30 mL of chloroform. The obtained organic layer was rinsed two times with water, followed by distilling a solvent off, thereby obtaining 0.96 g of the target triphenylsulfonium 1,1-difluoro-2-(valeryloxy)ethanesulfonate.

المصدر