تفاعل #1596998

معادلة التفاعل

5-aminosalicylic acid

4-fluorobenzyl bromide

→

5-(4-fluorobenzyl)aminosalicylic acid

المردود 56.4%

ظروف التفاعل

المعالجة

1. 1
   أخرىin Synthesis Example 1

الإجراء التجريبي

By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-fluorobenzyl bromide (740 mg, 3.92 mmole), 480 mg (44% yield) of 5-(4-fluorobenzyl)aminosalicylic acid was obtained as a white solid.:mp>210° C. (decompose).

المصدر