تفاعل #1596997

معادلة التفاعل

5-aminosalicylic acid

4-(trifluoromethyl)benzyl chloride

→

5-(4-(trifluoromethyl)benzyl)aminosalicylic acid

المردود 50.3%

ظروف التفاعل

المعالجة

1. 1
   أخرىin Synthesis Example 1

الإجراء التجريبي

By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-(trifluoromethyl)benzyl chloride (760 mg, 3.92 mmole), 510 mg (50% yield) of 5-(4-(trifluoromethyl)benzyl)aminosalicylic acid was obtained as a white solid.:mp>188° C. (decompose).

المصدر