تفاعل #159686

معادلة التفاعل

5-chloro-2-(3-(3-fluorophenoxy)azetidin-1-yl)nicotinic acid

methyl 6-(1-aminocyclopropyl)nicotinate hydrochloride

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title compound ( D159 )

المردود 24.2%

methyl 6-(1-(5-chloro-2-(3-(3-fluorophenoxy)azetidin-1-yl)nicotinamido)cyclopropyl)nicotinate

المردود 24.2%

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الإجراء التجريبي

The title compound (D159) (22.4 mg) was prepared according to the experimental procedure described in Description 146 starting from 5-chloro-2-(3-(3-fluorophenoxy)azetidin-1-yl)nicotinic acid (D103) (60 mg, 0.186 mmol) and methyl 6-(1-aminocyclopropyl)nicotinate hydrochloride (D12) (28.5 mg, 0.186 mmol).

المصدر