تفاعل #159378

معادلة التفاعل

4-methyl-3-nitrophenol

butyl bromide

sodium carbonate

DMF

→

4-Butoxy-1-methyl-2-nitrobenzene

المذيبات

MTBE

ظروف التفاعل

المعالجة

1. 1
   أخرىThe cooled reaction solution
2. 2
   غسيلwashed twice each with water and sodium hydroxide solution
3. 3
   أخرىThe organic phase was dried
4. 4
   تركيزconcentrated
5. 5
   أخرىThe product with the molecular weight of 209.25 (C11H15NO3) was obtained in this way

الإجراء التجريبي

A mixture of 4-methyl-3-nitrophenol (10.0 g), butyl bromide (9.4 g), sodium carbonate (6.9 g) and DMF (50 mL) was heated at 80° C. for 7 hours. The cooled reaction solution was diluted with MTBE and washed twice each with water and sodium hydroxide solution. The organic phase was dried and concentrated. The product with the molecular weight of 209.25 (C11H15NO3) was obtained in this way; MS (ESI): 210 (M+H+).

المصدر