تفاعل #157010

معادلة التفاعل

4-chloro-3-nitropyridine

3-N-Boc-amino piperidine

diisopropylethylamine

→

tert-butyl 1-(3-nitropyridin-4-yl)piperidin-3-ylcarbamate

المردود 89.0%

ظروف التفاعل

الإجراء التجريبي

The method of Example 1 was followed using 1 eq each of 4-chloro-3-nitropyridine, 3-N-Boc-amino piperidine and diisopropylethylamine yielding tert-butyl 1-(3-nitropyridin-4-yl)piperidin-3-ylcarbamate, (89%). LCMS (m/z): 323.1 (MH+); LC Rt=2.13 min.

المصدر