تفاعل #1559843

معادلة التفاعل

2,3-dichloro-6-methoxyquinoline

Intermediate 4

2,3-dichloro-6-methoxyquinoline

4-borono-3-fluorobenzoic acid

→

desired product

4-(3-chloro-6-methoxyquinolin-2-yl)-3-fluorobenzoic acid

ظروف التفاعل

المعالجة

1. 1
   أخرىAn aqueous/EtOAc workup was performed followed by purification by silica gel column (PE/EtOAc=1/1)

الإجراء التجريبي

Scheme 3: starting from 2,3-dichloro-6-methoxyquinoline (Intermediate 4) and 4-borono-3-fluorobenzoic acid. An aqueous/EtOAc workup was performed followed by purification by silica gel column (PE/EtOAc=1/1) to give the desired product.

المصدر