تفاعل #1541934

ord-038bffab496c45838222c722c8aba08d

معادلة التفاعل

[K]
potassium
CC(C)(C)OC(=O)C(C#N)C=O
3-oxo-2-cyanopropanoic acid t-butyl ester
[Cl-].c1ccc([S+](c2ccccc2)c2ccccc2)cc1
triphenylsulfonium chloride
O
water
→
CC(C)(C)OC(=O)C(C#N)C=O.c1ccc([S+](c2ccccc2)c2ccccc2)cc1
3-oxo-2-cyanopropanoic acid t-butyl ester triphenylsulfonium salt
المردود 79.0%

المتفاعلات

—
solution
[K]
potassium
CC(C)(C)OC(=O)C(C#N)C=O
3-oxo-2-cyanopropanoic acid t-butyl ester
[Cl-].c1ccc([S+](c2ccccc2)c2ccccc2)cc1
triphenylsulfonium chloride
O
water

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

COMP CD-8 was prepared similar to COMP CD-7 at 79% yield from potassium salt of 3-oxo-2-cyanopropanoic acid t-butyl ester (2.07 g, 10 mmol) and 50% solution of triphenylsulfonium chloride in water (5.96 g, 10 mmol) as a yellow color, light weight (fluffy) crystalline material.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07482113B2uspto-grants-2009_01