تفاعل #1539564

معادلة التفاعل

5-Acetoxy-4,6-di-tert-butyl-2-(1-octenyl)benzofuran

→

5-acetoxy-4,6-di-tert-butyl-2-octylbenzofuran

المردود 96.0%

المذيبات

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   ترشيحAfter filtering off the Pd on carbon
2. 2
   تركيزthe filtrate was concentrated under vacuum
3. 3
   أخرىThe concentrate was purified by silica gel chromatography (10% ethyl acetate in n-hexane)

الإجراء التجريبي

5-Acetoxy-4,6-di-tert-butyl-2-(1-octenyl)benzofuran (3.1 g) was dissolved in ethyl acetate containing 10% acetic acid (50 ml) and, after addition of 10% Pd on carbon (0.3 g), the solution was stirred under a hydrogen atmosphere for 3 h. After filtering off the Pd on carbon, the filtrate was concentrated under vacuum. The concentrate was purified by silica gel chromatography (10% ethyl acetate in n-hexane) to afford 5-acetoxy-4,6-di-tert-butyl-2-octylbenzofuran [2.95 g (yield, 96%)] as a colorless oil.

المصدر