تفاعل #1526156

معادلة التفاعل

methoxycarbonyl isocyanate

2-amino-4-methylbenzothiazole

→

methyl 4-(4-methylbenzothiazol-2-yl)allophanate

المردود 37.0%

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   تركيزThe solution was concentrated to one fifth the original volume
2. 2
   أخرىthe solid isolated by filtration

الإجراء التجريبي

Two and one half parts by weight of methoxycarbonyl isocyanate was added gradually with stirring to a solution of 4 parts by weight of 2-amino-4-methylbenzothiazole dissolved in 250 parts by weight of methylene chloride. The reaction mixture was stirred at room temperature for 12 hours. The solution was concentrated to one fifth the original volume and the solid isolated by filtration to give a 37% yield of methyl 4-(4-methylbenzothiazol-2-yl)allophanate having a melting point of 272°-280° with decomposition.

المصدر