تفاعل #1519094

معادلة التفاعل

4-Benzyloxybenzyl chloride

triphenyl phosphine

ether

→

4-benzyloxybenzyltriphenyl phosphonium chloride

المذيبات

toluene

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe precipitated phosphonium salt was collected by filtration
2. 2
   غسيلrinsed with ether and air
3. 3
   أخرىdried

الإجراء التجريبي

4-Benzyloxybenzyl chloride (1 g, 0.0043 moles) and triphenyl phosphine (1.127 g, 1 equivalent) in anhydrous toluene (20 mL) were refluxed under nitrogen for ˜8-10 hours. A white precipitate appeared in the reaction mixture. The reaction mixture was then cooled to room temperature and ether (100 mL) was added. The precipitated phosphonium salt was collected by filtration, rinsed with ether and air dried. Yield=0.55 g (25%). MALDI-TOF MS 459.51 obs. (459.54 calc.).

المصدر