تفاعل #1511328

معادلة التفاعل

(S)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidine-4-carboxylic acid

3′,4′-diaminobiphenyl-4-carbonitrile

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title compound

4-{2-[(1R)-1-Amino-2-hydroxyethyl]-1H-benzimidazol-5-yl}benzonitrile

ظروف التفاعل

المعالجة

1. 1
   أخرىThe residue was purified through an SCX cartridge
2. 2
   غسيلeluting with 0-60% MeCN in water

الإجراء التجريبي

The title compound was prepared according to Method 1 using (S)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidine-4-carboxylic acid and 3′,4′-diaminobiphenyl-4-carbonitrile (Preparation 82). The residue was purified through an SCX cartridge followed by reverse phase column chromatography eluting with 0-60% MeCN in water.

المصدر