تفاعل #1509618

معادلة التفاعل

methylphenidate HCl

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Methylphenidate

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   أخرىThe wet pellets are dried (Fluid Air Model#0050)
2. 2
   ترشيحsieved (30 mesh<Acceptable<20 mesh)

الإجراء التجريبي

In a preferred manufacturing process, methylphenidate HCl and microcrystalline cellulose (Avicel PH-101) are blended in a Hobart Mixer. Purified water is added to the dry mixture and the wet granulation is extruded (MG-55 Multi granulator). The extrudate is then spheronized into pellets (Caleva Model#SPH1250). The wet pellets are dried (Fluid Air Model#0050) and sieved (30 mesh<Acceptable<20 mesh).

المصدر